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The SYRMEP (SYnchrotron Radiation for MEdical Physics) beamline has been designed by Sincrotrone Trieste, in collaboration with the University of Trieste and the INFN, for research in medical diagnostic radiology, material science and life science applications. The use of monochromatic and laminar-shaped beams allows, in principle, an improvement of the clinical quality of images and a reduction of adsorbed dose (because of both monochromaticity and scatter reduction). Moreover, the spatial coherence of the SYRMEP source is used to overcome the poor absorption contrast of many biological samples, by the use of phase-contrast techniques.
A large number of different microimaging and microtomography experiments can be performed in different fields of material science (such as geology, vulcanology, cultural heritage and agrifood technology) and life science.

The light source is a bending magnet.

The beamline can work in monochromatic or white-beam configuration.

Research highlights

X-ray-based methods to model the release of a highly water-soluble drug from lipid microspheres

The present study deals with systems dedicated to oral administration and able to prolong or extend the delivery of drugs at predictable and reproducible rate, for a period defined by the control of their release kinetics. Several control drug delivery systems have been investigated, highlighting different release mechanisms.  P. Pivette “Controlled release of a highly hydrophilic drug from lipid microspheres obtained by prilling: analysis of drug and water diffusion processes based on X-ray methods”, Journal of Controlled Release 158, 393, (2012), doi: 10.1016/j.jconrel.2011.11.027.

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Quantitative analysis of X-ray microCT images of geomaterials.

X-ray  computed  microtomography  is  an excellent tool for the three-dimensional analysis of rock microstructure.
   D. Zandomeneghi et. al. Geosphere; December 2010; v. 6; no. 6;

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Advancements towards the implementation of clinical phase-contrast breast computed tomography at Elettra

   R. Longo et al., ”Advancements toward the implementation of clinical phase-contrast breast computed tomography at Elettra”, J. Synchrotron Rad. 26, 1343-53 (2019); doi.org/10.1107/S1600577519005502

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Physicists & chemists ally to bring back the forgotten secrets of ancient violin-makers

   G. Fiocco et al., ”Synchrotron radiation micro-computed tomography for the investigation of finishing treatments in historical bowed string instruments: issues and perspectives”, European Physical Journal Plus. 133, 525-34 (2018); doi.org/10.1140/epjp/i2018-12366-5

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Neanderthal features in old human dental remains from the Italian Peninsula

   C. Zanolli et al., ”The Middle Pleistocene (MIS 12) human dental remains from Fontana Ranuccio (Latium) and Visogliano (Friuli-Venezia Giulia), Italy. A comparative high resolution endostructural assessment, PLoS ONE 13(10): e0189773 (2018). doi: 10.1371/journal.pone.0189773

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Monochromatic beam

The optics is based on a double-crystal Si (111) monochromator which works in an energy range between 8 keV and 40 keV. The beamline provides at a distance of about 20 m from the source, a monochromatic or white, laminar-section X-ray beam with a maximum area of 120x4 mm2.
The horizontal acceptance covered by the light-port of the front-end is 7 mrad.
The available imaging techniques of the SYRMEP beamline are conventional absorption radiology and tomography, phase contrast imaging, diffraction enhanced imaging.

Proposal Submission

We invite users and collaborators to discuss thier proposals with the beamline local contacts well in advance before the submission deadline. This is a crucial step for a careful assesment of the experiment feasibility and may lead to improvements in the proposed experimental plan. In a restricted number of cases, when doubts arise about the suitability of your samples,  it may be possible for you to arrange a feasibility test. For more info, please visit the Info for users page

Call for proposals

The deadline for proposal submission for beamtime allocation from January 1st to June 30th, 2020 will be September 16th, 2019.

Last Updated on Wednesday, 09 October 2019 14:41