IUVS Beamline
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Research Highlights ![]() Structural specificity of groove binding mechanism between imidazolium-based ionic liquids and DNAThe predicted capability of Ionic Liquids (ILs) in stabilizing the native structure of nucleic acids is relevant in biotechnology, especially for DNA storage and handling. Read More![]() Single-atom substitution enables supramolecular diversity from dipeptide building blocksDipeptides are popular building blocks for supramolecular gels that do not persist in the environment and may find various applications. Read More![]() Unlocking the Power of Resonance Raman Spectroscopy: the Case of Amides in Aqueous SolutionBy employing state-of-the-art QM/MM methods combined with synchrotron–based UV Resonance Raman spectroscopy, a protocol is proposed to interpret and reliably predict Resonance Raman spectra for amide systems in water. Read More![]() In Competition for Water: Hydrated Choline Chloride:Urea vs Choline Acetate:Urea Deep Eutectic Solvents
The replacement of chloride with acetate makes possible the design of safer choline-based DESs.
![]() Hydrogen Bonding and Solvation of a Proline-Based Peptide by SR-UVRR
In polypeptide sequences, the amino acid proline (Pro) is considered to have a unique role in determining protein structure and folding. Multi-wavelength UV resonance Raman (UVRR) spectroscopy is a powerful method for investigating the hydrogen bonding in peptides and proteins containing Pro. ![]() Insight into the thermal stability of DNA in ionic liquids/water solutionsThe utility of ionic liquids (ILs) as alternative solvents for stabilizing and preserving the native structure of DNA over the long term may be envisaged for biotechnological and biomedical applications in the near future. Read More![]() Nanostructured liquid crystalline particles as delivery vectors for anticancer drug
Nanostructures liquid crystalline particles as delivery vectors for isofuranodiene: Characterization and in-vitro anticancer activity ![]() Structure of human telomere G-quadruplex in the presence of a model drug
G-rich DNA sequences are able to fold into structures called G-quadruplexes (G4).
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The peculiarity of IUVS is the specific kinematic region that can be investigated. IUVS beamline delivers photons with incident energy between 5 and 11 eV. The incident photons that are inelastically diffused by the sample can be analysed by exploiting the two different and complementary experimental set-up available on the beamline, i.e. UV Brillouin and UV Resonant Raman scattering instruments, in order to probe both the acoustic and optical phonons propagating in the system. This allows to acquire information about the structure and dynamics of the constituent matter over different length scales through the analysis of its collective and molecular vibrations. |
The almost-backscattering configuration of Brillouin setup, with scattering angle theta of 178 degree, allows an exchanged momentum range of 2*10-2-2*10-1nm-1, corresponding to 10-1000 µeV scattered energy. Therefore it can investigate a S(q,ω) kinematic region not accessible at present by other experimental techniques as Brillouin scattering with visible light, X-Ray scattering and neutron scattering.
The more recently realized experimental setup that enables to perform UV Resonant Raman spectroscopy using synchrotron radiation in the range of wavelengths 200-270 nm provides a fine tunable source in the deep-UV for mapping a wide resonance landscape range in different samples, from nanostructures and strongly correlated materials to biophysical and biochemical systems.
User's News
Proposal SubmissionWe invite users and collabrators to discuss thier proposals with the beamline local contacts well in advance before the submission deadline. This is crucial for a careful assesment of the experiment feasibility and may lead to improvements in the proposed experimental plan. In a restricted number of cases, when doubts arise about the suitability of your samples (sample absorption etc), it may be possible for you to arrange a test. Our website provides a wealth of informaiton on experiment feasibilty and proposal submission. For more info, please vist the IUVS Users section. |
Call for proposalsThe deadline for proposal submission for beamtime allocation is to be announced |