last update June 24, 2010, at 12:19 AM
by Silvia Onesti

Keynote lecturers

  • John Diffley - Cancer Research UK
  • Andres Aguilera - Universidad de Sevilla-CSIC
  • Alan Lehmann - University of Sussex (Sponsored by SIBBM)

Final Programme

Wednesday, 30 June

10.00-14.00 Registration
14.00-14.30 Welcome and commemoration of Arturo Falaschi
DNA replication and replication dynamics
14.30-14.50 Laura Marchetti: Homeotic proteins participate in the function of human-DNA replication origins.
14.50-15.40 Keynote Lecture
John Diffley: Mechanism and Regulation of DNA Replication during the Cell Cycle and in Response to DNA Damage
15.40-16.00 Silvia Onesti: Structural basis of the MCM helicase activity
16.00-16.30 Alessandro Vindigni: Understanding the multiple roles of RecQ helicases in DNA replication
16.3017.00 Coffee break
17.00-17.30 Luca Pellegrini: Structural biology of proteins important for DNA replication and repair
17.30-18.00 Vincenzo Costanzo: The role of Rad51 in DNA replication
18.00-18.20 Francesca Carlomagno: Protein NCOA4 is a novel inhibitor of DNA replication in mammals and Xenopus laevis
18.20-18.40 Federica Lo Sardo: Genetic and epigenetic heritability: PcG system and replication
18.40-19.00 Chiara Lanzuolo: Timing of PcG mediated epigenetic inheritance through S phase in Drosophila melanogaster
19.30 Dinner buffet


Thursday, 1 July

DNA repair and recombination
9.009.50 Keynote Lecture
Alan Lehmann: Regulation of translesion synthesis in human cells
9.50-10.20 Miria Stefanini: NER-defective hereditary disorders
10.20-10.40 Donata Orioli: Insights into genotype-phenotype relationships in the repair/transcription syndrome Trichothiodystrophy
10.40-11.00 Ennio Prosperi: Investigating the role of p300 and CBP in nucleotide excision repair: interaction with NER factors
11.0011.20 Coffee break
11.20-11.40 Marco Muzi-Falconi: Converging mechanisms for the full activation of the DNA damage checkpoint
11.40-12.00 Magda Granata: Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle regulated by CDK1 activity
12.00-12.20 Achille Pelliccioli: Mechanisms and factors involved in turning off the DNA damage checkpoint
12.20-12.40 Pietro Pichierri: Functional relevance of ATR phosphorylation of the Werner syndrome protein in response to replication stress
12.40-13.00 Silvia Baldari: Mechanisms of genome stability at common fragile sites - Regulation of checkpoint activation
13.0014.30 Lunch
14.3016.00 Poster session
16.00-16.20 Evandro Panico: Yeast Mph1 is an important factor for the fine tuning of recombinational DNA repair under replicative stress
16.20-16.40 Emanuele Crespan: DNA polymerase Lambda specifically bridges and extends DNA ends containing microhomology regions and is supported by interaction with the 9-1-1 complex
16.40-17.00 Maria Ciaramella: A novel pathway for Holliday junction resolution revealed by archaeal reverse gyrase
17.0017.20 Coffee break
17.20-17.40 Adriana La Volpe: Roles of the BRCA1 and FANCD2 orthologs in meiosis and genome stability in Caenorhabditis elegans
17.40-18.00 Aurora Storlazzi: Sordaria macrospora: a model system to study pairing of meiotic chromosomes
18.00-18.30 Margherita Bignami: Biochemical and functional characterization of MUTYH mutations associated with Familial Adenomatous Polyposis
18.30-18.50 Maria Teresa Russo: Oxidative damage, aging and mitochondrial DNA stability: is there a relationship
20.30 Conference dinner


Friday, 2 July

Genome instability
9.009.50 Keynote Lecture
Andreas Aguilera: Recombination-mediated genome instability: from transcription to nucleotide excision repair
09.50-10.10 Alessandra Montecucco: Pre-mRNA processing factors meet the DNA damage responses
10.10-10.30 Corrado Santocanale: Addressing the role of human Cdc7 kinase in the DNA replication checkpoint
10.30-10.50 Ivana Murfuni: Investigation of the MUS81-dependent pathway in the absence of the replication checkpoint and analysis of its regulation
10.5011.20 Coffee break
11.20-11.40 Francesco Merolla: Cell cycle dependent regulation of CCDC6 gene product: functional interaction with mitotic kinases and the catalytic subunit of Protein Phosphatase 4
11.40-12.00 Thomas Carzaniga: Polynucleotide phosphorylase has 3 to 5 exonuclease and template-independent DNA polymerase activities on single-stranded DNA in bacteria
12.00-12.30 Maurizio Gatti: Drosophila telomeres: structure, evolution and role in cell cycle control
12.3012.40 Closing Remarks

Practical information about oral/poster presentation

In preparing your poster/oral presentation, please take note of the following points:

  • Presentations are allowed in PowerPoint only and should be saved as .ppt files in the COMPATIBILITY FOR THE POWER POINT 97-2003 mode (this is the native format of PowerPoint2004 but must be selected in the "save as" menu for later versions).
  • Presentations should be saved on a USB pen drive (SANITIZED FOR VIRUSES!) or CD and uploaded on the Meeting computer the day of the presentation. Both Mac and PC platforms will be available. No private laptop is allowed unless deemed strictly necessary because of large files or complex media type (movies, etc.). In such a case, the speaker is invited to warn the technical assistance in fair advance, in order to allow time for preparing and checking the compatibility of the laptop and the projector connections.
  • Posters will be mounted on vertical panels (100cm width x 200 cm height). The recommended size for the poster is therefore A0 or smaller.