SYRMEP

The SYRMEP (SYnchrotron Radiation for MEdical Physics) beamline has been designed by Sincrotrone Trieste, in collaboration with the University of Trieste and the INFN, for research medical diagnostic radiology, material science and life science applications. The use of monochromatic and laminar-shaped beams allows, in principle, an improvement of the clinical quality of images and a reduction of adsorbed dose (because of both monochromaticity and scatter reduction). Moreover, the spatial coherence of the SYRMEP source is used to overcome the poor absorption contrast of many biological samples, by the use of phase-contrast techniques.
A large number of different microimaging and microtomography experiments can be performed in different fields of material science (such as geology, vulcanology, cultural heritage and agrifood technology) and life science.

The light source is a bending magnet.

The beamline can work in monochromatic or white-beam configuration.

Research highlights

Mammography with Synchrotron Radiation

To prospectively evaluate the diagnostic contribution of mammography with synchrotron radiation in patients with questionable or suspicious breast abnormalities identified at combined digital mammography (DM) and ultrasonography (US).
E. Castelli et al., Volume 259: Number 3—June 2011

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A combination of modern physics tools reveals the oldest dental filling, dating back to the Stone Age

In the present study, several research groups with different expertize have adopted a multi-disciplinary approach providing the earliest direct evidence of a therapeutic dental filling.
   F. Bernardini (“Beeswax as Dental Filling on a Neolithic Human Tooth", PLoS ONE 7, e44904 (2012)"

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X-ray-based methods to model the release of a highly water-soluble drug from lipid microspheres

The present study deals with systems dedicated to oral administration and able to prolong or extend the delivery of drugs at predictable and reproducible rate, for a period defined by the control of their release kinetics. Several control drug delivery systems have been investigated, highlighting different release mechanisms.  P. Pivette “Controlled release of a highly hydrophilic drug from lipid microspheres obtained by prilling: analysis of drug and water diffusion processes based on X-ray methods”, Journal of Controlled Release 158, 393, (2012), doi: 10.1016/j.jconrel.2011.11.027.

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Quantitative analysis of X-ray microCT images of geomaterials.

X-ray  computed  microtomography  is  an excellent tool for the three-dimensional analysis of rock microstructure.
   D. Zandomeneghi et. al. Geosphere; December 2010; v. 6; no. 6;

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Internal architecture and micro-biomechanical behaviour of the Neanderthal Kebara 2 hyoid bone compared with modern human hyoids: implication for speech capacity

This work represents a decisive step forward supporting the hypothesis that the Neanderthals engaged in speech
   Ruggero D’Anastasio, , ”Micro-Biomechanics of the Kebara 2 Hyoid and Its Implications for Speech in Neanderthals”, PLoS ONE 8, e82261 (2013); DOI: 10.1371/journal.pone.0082261

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Monochromatic beam

The optics is based on a double-crystal Si (111) monochromator which works in an energy range between 8 keV and 35 keV. The beamline provides at a distance of about 20 m from the source, a monochromatic, laminar-section X-ray beam with a maximum area of 120x4 mm2.
The horizontal acceptance covered by the light-port of the front-end is 7 mrad.
The available imaging techniques of the SYRMEP beamline are conventional absorption radiology and tomography, phase contrast imaging, diffraction enhanced imaging.

White beam

In the withe beam configuration the X-ray beam from the ring is intercepted before the monochromator and absorption and phase contrast radiography and tomography are available in a dedicated end-station.


User Area

Proposal Submission

We invite users and collaborators to discuss thier proposals with the beamline local contacts well in advance before the submission deadline. This is a crucial step for a careful assesment of the experiment feasibility and may lead to improvements in the proposed experimental plan. In a restricted number of cases, when doubts arise about the suitability of your samples,  it may be possible for you to arrange a feasibility test. For more info, please visit the Info for users page


Call for proposals

The deadline for proposal submission for beamtime allocation from January 1st to June 30th, 2017 will be September 15th, 2016.


Last Updated on Friday, 24 June 2016 09:09